Introduction and historical perspectives / Sumner J. Yaffe and Jacob V. Aranda -- Clinical pharmacokinetics in infants and children / Edmund V. Capparelli -- Drug action and therapy in the infant and child / Ralph E. Kauffman -- Drug metabolism and disposition in infants and children / Anders Rane -- Pharmacogenetics, pharmacogenomics, and pharmacoproteomics / J. Steven Leeder -- Compliance with pediatric medication regimens / Hakan Ergun and Daniel A.C. Frattarelli -- Clinical trials involving children: history, rationale, and technical considerations / Steven Hirschfeld -- Ethics of drug research in pediatric populations / Sanford N. Cohen and Bruce L. Russell -- Therapeutic drug monitoring / Alexander A. Vinks and Philip D. Walson -- Drug formulations / Milap C. Nahata -- Developmental toxicology / Donald R. Mattison and John F. Young --Placental transfer of drugs / Rada Boskovic and Gideon Koren -- Principles of neonatal pharmacology / Jeffrey L. Blumer and Michael D. Reed -- Perinatal origins of adult defects in drug metabolism / Bernard H. Shapiro -- Renal function and excretion of drugs in the newborn / John N. van den Anker -- The excretion of drugs and chemicals in human milk / Cheston M. Berlin, Jr. -- Drugs for hyperbilirubinemia / David K. Stevenson ... [et al.] -- Drugs and lung development / Alan H. Jobe -- Pharmacologic treatment of neonatal apnea / Jose M. Lopez and Jacob V. Aranda -- Drugs and perinatal brain injury / Maria Delivoria-Papadopoulos, Agustin Legido, and Om Prakash Mishra -- Antiretroviral pharmacology in pregnant women and newborns / Mark Mirochnick -- Therapeutic applications in pediatric intensive care / Mary Lieh-Lai and Ashok Sarnaik -- Drug therapy in the pediatric emergency department / Shannon F. Manzi and Michael W. Shannon --Drug therapy in the adolescent / Ian M. Paul and Richard L. Levine -- Topical medications / Fasahat H. Hamzavi and George J. Murakawa -- Ophthalmologic drugs in infants and children / John D. Roarty -- Sulfonamides / Chokechai Rongkavilit ... [et al.] -- Penicillins, beta-lactamase inhibitors, cephalopsporins and other beta-lactams / Sumathi Nambiar and William J. Rodriguez -- Aminoglycosides and glycopeptides / Matthijs de Hoog and John N. van den Anker -- Macrolides, chloramphenicol, and tetracyclines / Basim I. Asmar and Nahed M. Abdel-Haq -- Anthelminthic drugs in children / George C.F. Hsieh, Vincent C. Fan, and Peter J. Hotez -- Antituberculosis drugs / Alexander O. Tuazon -- Antifungal agents / William J. Steinbach and John R. Perfect -- Antiviral drugs / Charles G. Prober and David W. Kimberlin -- Anticonvulsants / Victoria Tutag Lehr, Harry T. Chugani, and Jacob V. Aranda --Psychopharmacology in children and adolescents / Julio Licinio -- Antihistamines / Sanaa A. Mahmoud and Sami L. Bahna -- Antiasthmatics / Glenn J. Whelan, Joseph D. Spahn, and Stanley J. Szefler -- Antipyretics / John T. Wilson and Margaret Ann Springer -- Cardiovascular drugs / Eli Zalzstein and Rafael Gorodischer -- Diuretics / Jean-Pierre Guignard -- Clinical pharmacology of antineoplastic drugs / Stacey L. Berg and David G. Poplack -- Immunosuppressive and immunomodulatory drugs / Nenna R. Gupta ... [et al.] -- Analgesic agents / Sinno H.P. Simons, Brian J. Anderson, and Dick Tibboel -- Local anesthetics for infants and children / Santhanam Suresh and Charles J. Cot? -- Nonsteroidal antiinflammatory drugs / Sylvain Chemtob -- Antihypertensive agents / Thomas C. Wells and Mohammed Ilyas -- Gastrointestinal drugs / Laura P. James ... [et al.] --Glucocorticoids / Evangelia Charmandari, Tomoshige Kino, and George P. Chrousos -- Insulin and diabetes mellitus / Tania S. Burgert and William Tamborlane -- Thyroid hormones / Delbert A. Fisher -- Growth hormone / Harvey J. Guyda -- Hematologic agents / Alfred A. Alvarez, Darlene A. Calhoun, and Robert D. Christensen -- Nutrient Supplements / Mary Frances Picciano, Carolyn S. Chung, and Paul M. Coates -- Childhood vaccines / David W. Scheifele -- Epidemiology of adverse drug effects / Louis Vernacchio and Allen A. Mitchell -- Medication errors / George H. Lambert, Marc G. Sturgill, and Diane D. Cousins -- Pediatric poisonings and antidotes / Suzanne R. White -- Use of herbal products in children: risks and unproven benefits / Wayne R. Snodgrass -- Neonatal abstinence syndromes / Loretta Finnegan and Stephen R. Kandall -- Drug formulary for the newborn / Marianne Lulic-Botica, Kevin Biglin, and Jacob V. Aranda -- Pediatric Drug Formulary / Shannon F. Manzi, Alana Arnold, and Al Patterson.