Number of the records: 1
Metabolomics: From Fundamentals to Clinical Applications
Title statement Metabolomics: From Fundamentals to Clinical Applications [electronic resource] / edited by Alessandra Sussulini. Publication Cham : Springer International Publishing : Imprint: Springer, 2017. Phys.des. X, 350 p. 56 illus., 54 illus. in color. online resource. ISBN 9783319476568 Edition Advances in Experimental Medicine and Biology, ISSN 0065-2598 ; 965 Contents Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics . Notes to Availability Přístup pouze pro oprávněné uživatele Another responsib. Sussulini, Alessandra. Another responsib. SpringerLink (Online service) Subj. Headings Life sciences. * Gene therapy. * Medical genetics. * Metabolism. Form, Genre elektronické knihy electronic books Country Německo Language angličtina Document kind Electronic books URL Plný text pro studenty a zaměstnance UPOL 
book
This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.
Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics .
Number of the records: 1