Number of the records: 1  

protein NLRP3

  1. Topical termprotein NLRP3
    See linkCold Autoinflammatory Syndrome 1 Protein (UF)
    NACHT, LRR and PYD Domains-Containing Protein 3 (UF)
    NLRP3 protein (UF)
    NLRP3 Protein (UF)
    See alsoNLR proteiny
    inflamasomy (RT)
    periodické syndromy asociované s kryopyrinem (RT)
    Linking entryNLR Family, Pyrin Domain-Containing 3 Protein
    ConspectD12. - 644. - 360. - 539. - 250
    NoteAn NLR protein that contains an N-terminal PYRIN DOMAIN and ATP-binding site and 9 C-terminal LEUCINE-rich repeats; it is expressed primarily by MACROPHAGES. It is a core component of the INFLAMMASOME and directs its assembly in response to pathogen infection and damage-associated stimuli. Mutations in the NLRP3 gene are associated with FAMILIAL COLD AUTOINFLAMMATORY SYNDROME.
    DatabaseMESH
    References (3) - MESH
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Number of the records: 1  

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