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Antimicrobial photodynamic inactivation and antitumor photodynamic therapy with fullerenes
Title statement Antimicrobial photodynamic inactivation and antitumor photodynamic therapy with fullerenes / Lucas F. de Freitas, Michael R. Hamblin. [elektronický zdroj] Publication San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) : Morgan & Claypool Publishers, [2016] Distribution Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2016] Phys.des. 1 online resource (various pagings) : illustrations (some color). ISBN 9781681742472 (online) 9781681741192 mobi Edition [IOP release 2] IOP concise physics, ISSN 2053-2571 Note "Version: 20160401"--Title page verso. "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. Internal Bibliographies/Indexes Note Includes bibliographical references. Contents Preface -- 1. Introduction -- 2. Fullerenes -- 3. Resonant energy transfer -- 4. Photo-induced charge transfer -- 5. Fullerenes as photosensitizers -- 6. Chemical modifications Content note 7. Examples of the synthesis of monocationic and polycationic fullerene derivatives -- 7.1. Synthesis of hexa-anionic fullerene derivatives -- 7.2. Synthesis of mono- or polycationic fullerene derivatives -- 7.3. Synthesis of chromophore-linked fullerene derivatives -- 7.4. The photophysics and photochemistry of fullerenyl molecular micelles and chromophore-fullerene conjugates -- 7.5. Synthesis of liposomal or micellar fullerenes. 8. Photodynamic therapy -- 8.1. Traditional photosensitizers -- 9. Photosensitizer formulations for fullerene-mediated PDT -- 10. In vitro anti-cancer PDT with fullerenes -- 11. In vivo PDT for cancer -- 12. Antibiotic resistance and viral infections -- 13. General aspects of photodynamic inactivation of bacteria -- 14. In vitro antimicrobial PDT with fullerenes -- 15. In vivo antimicrobial PDT with fullerenes -- 16. Conclusions. Notes to Availability Přístup pouze pro oprávněné uživatele Audience Advanced biomedical physicists, biooptics, nanotechnologies. Note Způsob přístupu: World Wide Web.. Požadavky na systém: Adobe Acrobat Reader. Another responsib. Morgan & Claypool Publishers, Institute of Physics (Great Britain), Subj. Headings Fullerenes - Therapeutic use. * Photochemotherapy. * Cancer - Photochemotherapy. * Applied Optics. * Biophysics. * Nanotechnology. * TECHNOLOGY & ENGINEERING / Nanotechnology & MEMS. * SCIENCE / Life Sciences / Biophysics. * TECHNOLOGY & ENGINEERING / Optics. MeSH Fullerenes - therapeutic use. * Photochemotherapy. * Bacterial Infections - drug therapy. * Neoplasms - therapy. Form, Genre elektronické knihy electronic books Country Kalifornie Language angličtina Document kind Electronic books URL Plný text pro studenty a zaměstnance UPOL book
This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.
Preface -- 1. Introduction -- 2. Fullerenes -- 3. Resonant energy transfer -- 4. Photo-induced charge transfer -- 5. Fullerenes as photosensitizers -- 6. Chemical modifications7. Examples of the synthesis of monocationic and polycationic fullerene derivatives -- 7.1. Synthesis of hexa-anionic fullerene derivatives -- 7.2. Synthesis of mono- or polycationic fullerene derivatives -- 7.3. Synthesis of chromophore-linked fullerene derivatives -- 7.4. The photophysics and photochemistry of fullerenyl molecular micelles and chromophore-fullerene conjugates -- 7.5. Synthesis of liposomal or micellar fullerenes8. Photodynamic therapy -- 8.1. Traditional photosensitizers -- 9. Photosensitizer formulations for fullerene-mediated PDT -- 10. In vitro anti-cancer PDT with fullerenes -- 11. In vivo PDT for cancer -- 12. Antibiotic resistance and viral infections -- 13. General aspects of photodynamic inactivation of bacteria -- 14. In vitro antimicrobial PDT with fullerenes -- 15. In vivo antimicrobial PDT with fullerenes -- 16. Conclusions.
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