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Pharmaco-imaging in drug and biologics development

  1. Title statementPharmaco-imaging in drug and biologics development : fundamentals and applications / Brian R. Moyer, Narayan P.S. Cheruvu, Tom C.-C. Hu, editors
    PublicationNew York, NY : Springer, 2014
    Phys.des.1 online zdroj (xvii, 401 stran) : ilustrace (některé barevně)
    ISBN9781461482475 (online ; pdf)
    146148247X
    EditionAAPS advances in the pharmaceutical sciences series ; 8
    NoteObsahuje rejstřík
    ContentsImaging Platforms and Drug Development: An Introduction / Brian R. Moyer -- Imaging in Drug Development: Animal Models, Handling and Physiological Constraints / David B. Stout -- Considerations for Preclinical Laboratory Animal Imaging Center Design, Setup, and Management Suitable for Biomedical Investigation for Drug Discovery / Brenda A. Klaunberg and H. Douglas Morris -- Pharmaco-Imaging in Translational Science and Research / Immanuel Freedman -- The Role of Pharmacokinetics and Allometrics in Imaging: Practical Issues and Considerations / Brian R. Moyer -- Quantitative Imaging Using Autoradiographic Techniques / Eric G. Solon and Brian R. Moyer -- Preclinical Imaging in Oncology: Considerations and Recommendations for the Imaging Scientist / Daniel P. Bradley and Tim Wyant -- Use of Radiolabelled Leukocytes for Drug Evaluation in Man / Chrystalla Loutsios, Neda Farahi, Charlotte Summers, Prina Ruparelia, Jessica White [and 9 others] -- Application of Bioluminescence Imaging (BLI) to the Study of the Animal Models of Human Infectious Diseases / Hana Golding and Marina Zaitseva -- Preclinical Imaging in BSL-3 and BSL-4 Environments: Imaging Pathophysiology of Highly Pathogenic Infectious Diseases / Lauren Keith, Svetlana Chefer, Laura Bollinger, Jeffrey Solomon [and 4 others] -- Magnetic Resonance as a Tool for Pharmaco-Imaging / Brian R. Moyer, Tom C.-C. Hu, Simon Williams and H. Douglas Morris -- Technologies and Principles of Mass Spectral Imaging / Kevin A. Douglass, Demian R. Ifa and Andre R. Venter -- Regulatory Considerations Involved in Imaging / Brian R. Moyer, Narayan P. S. Cheruvu and Tom C.-C. Hu.
    Notes to AvailabilityPřístup pouze pro oprávněné uživatele
    NoteZpůsob přístupu: World Wide Web
    DefektyeBooks on EBSCOhost
    Another responsib. Moyer, Brian R. (editor)
    Cheruvu, Narayan P. S. (editor)
    Hu, Tom C.-C. (editor)
    Subj. Headings farmaceutický průmysl pharmaceutical industry * vývoj léčiv drug development * analýza léčiv drug analysis
    Form, Genre elektronické knihy electronic books
    Conspect615 - Farmacie. Farmakologie
    UDC 615.012:001.891 , 615.07 , 615:338.45 , (0.034.2:08)
    CountryNew York
    Languageangličtina
    Document kindElectronic sources
    URLhttp://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=662353
    book

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    Advances in drugs and biologics to mitigate or cure some of nature's most complex medical problems have been incredible to behold. These accomplishments are due to the actions of a wide theatre of participants from biologists, pharmacologists, geneticists, chemists and manufacturers, molecular biologists, toxicologists, clinicians, nurses, program managers, quality assurance personnel, regulatory professionals and a new group of innovators the Imaging Scientists. Imaging has grown from the microscopy sections put on slides with special stains to now in vivo slices created with innovative physics, imaging tracers and contrast agents, and incredibly fast and accurate computational systems. The world of biology has become one of witnessing the actions of drugs and biologics through the window of mechanical and electrical engineering creating instruments and reporter molecules that can help us see into our bodies and paint them with medical information needed to resolve disease. This book will inspire imagination and elicit even more innovations in the development of new and novel drugs and biologics through imaging.

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