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DNA repair and cancer
Title statement DNA repair and cancer : from bench to clinic / editors, Srinivasan Madhusudan, David M. Wilson III. Publication Boca Raton : Taylor & Francis, 2013 Phys.des. 1 online zdroj (xvii, 688 stran) : ilustrace (některé barevně) ISBN 9781466577442 (online ; pdf) 1466577444 Internal Bibliographies/Indexes Note Obsahuje bibliografické odkazy a rejstřík Contents Overview of DNA repair pathways / Deborah L. Croteau and Vilhelm A. Bohr -- Longevity assurance by genome maintenance / Paul Hasty, Yousin Suh and Jan Vijg -- Genetic instability of cancer : biological predictions and clinical implications / Robert A. Beckman -- Radiation induced DNA damage, repair, and therapeutics / Lynn Harrison -- Chemotherapeutic alkylating agents in cancer treatment / Tracey D. Bradshaw -- O6-methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy / Bernd Kaina and Markus Christmann -- DNA mismatch repair : it's role in human carcinogenesis and as a predictive and/or prognostic biomarker for cancer therapy / Timothy J. Kinsella -- DNA base excision repair therapeutics : summary of targets with a focus on APE1 / Melissa L. Fishel, Carlo Vascotto and Mark R. Kelley -- Nucleotide excision repair : DNA repair capacity variability and cancer susceptibility / Li-E Wang and Qingyi Wei -- Fanconi anemia, interstrand cross-link repair, and cancer / Taraswi Banerjee, Sanjay Kumar Bharti and Robert M. Brosh, Jr -- Functions of translesion DNA polymerases : implications for cancer risk and opportunities as therapeutic targets / Kinrin Yamanaka and R. Stephen Lloyd -- P53 in DNA damage, repair and cancer therapeutics / Aditi Gurkar, Kiki Chu and Sam W. Lee -- ATM/ATR cell cycle checkpoints : mechanisms and manipulation in cancer therapy / Marie Fernet, Sara Chiker and Janet Hall -- The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy / Laura J. Eccles [and others] -- PARP and PARP inhibitor therapeutics / Nicola J. Curtin -- Tumor genetics and personalized medicine / Mary Ellen Urick and Daphne W. Bell -- The tumor microenvironment and DNA repair : implications for cancer progression and treatment / Norman Chan, Shaqil Kassam and Robert G. Bristow -- Early phase clinical trials using DNA repair inhibitors : lessons learnt / Miranda Payne and Mark Middleton. Notes to Availability Přístup pouze pro oprávněné uživatele Note Způsob přístupu: World Wide Web Defekty eBooks on EBSCOhost Another responsib. Madhusudan, Srinivasan (editor) Wilson David M. (editor) Subj. Headings maligní nádorová onemocnění cancer * DNA (nukleová kyselina) deoxyribonucleic acid * účinky léků drug effects * dědičné nádorové syndromy hereditary neoplasic syndromes Form, Genre elektronické knihy electronic books Conspect 616 - Patologie. Klinická medicína UDC 615.015 , 577.113.8 , 577.21 , 616-006.04-056.7-008.6 , 616-006.04 , (0.034.2:08) Country Florika Language angličtina Document kind Electronic sources URL http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=581357 book
Overview of DNA repair pathways / Deborah L. Croteau and Vilhelm A. Bohr -- Longevity assurance by genome maintenance / Paul Hasty, Yousin Suh and Jan Vijg -- Genetic instability of cancer : biological predictions and clinical implications / Robert A. Beckman -- Radiation induced DNA damage, repair, and therapeutics / Lynn Harrison -- Chemotherapeutic alkylating agents in cancer treatment / Tracey D. Bradshaw -- O6-methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy / Bernd Kaina and Markus Christmann -- DNA mismatch repair : it's role in human carcinogenesis and as a predictive and/or prognostic biomarker for cancer therapy / Timothy J. Kinsella -- DNA base excision repair therapeutics : summary of targets with a focus on APE1 / Melissa L. Fishel, Carlo Vascotto and Mark R. Kelley -- Nucleotide excision repair : DNA repair capacity variability and cancer susceptibility / Li-E Wang and Qingyi Wei -- Fanconi anemia, interstrand cross-link repair, and cancer / Taraswi Banerjee, Sanjay Kumar Bharti and Robert M. Brosh, Jr -- Functions of translesion DNA polymerases : implications for cancer risk and opportunities as therapeutic targets / Kinrin Yamanaka and R. Stephen Lloyd -- P53 in DNA damage, repair and cancer therapeutics / Aditi Gurkar, Kiki Chu and Sam W. Lee -- ATM/ATR cell cycle checkpoints : mechanisms and manipulation in cancer therapy / Marie Fernet, Sara Chiker and Janet Hall -- The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy / Laura J. Eccles [and others] -- PARP and PARP inhibitor therapeutics / Nicola J. Curtin -- Tumor genetics and personalized medicine / Mary Ellen Urick and Daphne W. Bell -- The tumor microenvironment and DNA repair : implications for cancer progression and treatment / Norman Chan, Shaqil Kassam and Robert G. Bristow -- Early phase clinical trials using DNA repair inhibitors : lessons learnt / Miranda Payne and Mark Middleton.
Number of the records: 1