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High-throughput screening methods in toxicity testing

  1. Title statementHigh-throughput screening methods in toxicity testing / edited by Pablo Steinberg
    PublicationHoboken, New Jersey : John Wiley & Sons Inc., [2013?]
    Phys.des.1 online zdroj
    ISBN9781118538180 (online ; pdf)
    Internal Bibliographies/Indexes NoteObsahuje bibliografické odkazy a rejstřík
    Notes to AvailabilityPřístup pouze pro oprávněné uživatele
    NoteZpůsob přístupu: World Wide Web
    DefektyeBooks on EBSCOhost
    Another responsib. Steinberg, Pablo (editor)
    Subj. Headings farmakologie pharmacology * testování léků drugs testing * testy toxicity toxicity tests
    Form, Genre elektronické knihy electronic books
    Conspect615 - Farmacie. Farmakologie
    UDC 615.01/.09 , 615.9:57.08 , 615.038 , (0.034.2:08)
    CountryNew Jersey
    Document kindElectronic sources


    "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--"This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"--

    pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.

Number of the records: 1