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Practical biostatistics

  1. Title statementPractical biostatistics : a user-friendly approach for evidence-based medicine / Mendel Suchmacher, Mauro Geller
    Personal name Suchmacher, Mendel (author)
    Edition statementFirst edition
    PublicationAmsterdam ; Boston : Elsevier/Academic Press, 2012
    Phys.des.1 online zdroj (xii, 236 stran) : ilustrace
    ISBN9780124157941 (online ; pdf)
    0124157947
    9780124158573
    0124158579
    Internal Bibliographies/Indexes NoteObsahuje bibliografické odkazy a rejstřík
    ContentsPart I : introduction. Study type determination -- Part II : observational studies. Determination of association strength between an exposure factor and an event in observational studies ; Increasing accuracy in observational studies -- Part III : step-by-step biostatistics of a clinical trial. Step 1 : investigator's hypothesis and expression of its corresponding outcome ; Step 2 : n estimation and n assessment of a published trial ; Step 3 : organization of variables and endpoints ; Step 4 : measures for results expression of a clinical trial ; Step 5 : determination of normality or non-normality of data distribution ; Step 6 : hypothesis testing ; Step 7 : correlating sample data with the general population 95% confidence interval -- Part IV : additional concepts in biostatistics. Individual and collective benefit and risk indexes inferable from intervention studies ; Statistical assessment of diagnostic tests for the clinic ; Systematic reviews and meta-analyses ; Correlation and regression ; Per protocol analysis and intention to treat analysis.
    Notes to AvailabilityPřístup pouze pro oprávněné uživatele
    NoteZpůsob přístupu: World Wide Web
    DefektyeBooks on EBSCOhost
    Another responsib. Geller, Mauro (author)
    Subj. Headings biometrika biometry * zdravotnická statistika medical statistics
    Form, Genre elektronické knihy electronic books
    Conspect57 - Obecná biologie
    UDC 57.087.1 , 311.3:614.1 , (0.034.2:08)
    CountryNizozemsko ; Spojené státy americké
    Languageangličtina
    Document kindElectronic sources
    URLhttp://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=457365
    View book information on page www.obalkyknih.cz

    book


    Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials.

    Part I : introduction. Study type determination -- Part II : observational studies. Determination of association strength between an exposure factor and an event in observational studies ; Increasing accuracy in observational studies -- Part III : step-by-step biostatistics of a clinical trial. Step 1 : investigator's hypothesis and expression of its corresponding outcome ; Step 2 : n estimation and n assessment of a published trial ; Step 3 : organization of variables and endpoints ; Step 4 : measures for results expression of a clinical trial ; Step 5 : determination of normality or non-normality of data distribution ; Step 6 : hypothesis testing ; Step 7 : correlating sample data with the general population 95% confidence interval -- Part IV : additional concepts in biostatistics. Individual and collective benefit and risk indexes inferable from intervention studies ; Statistical assessment of diagnostic tests for the clinic ; Systematic reviews and meta-analyses ; Correlation and regression ; Per protocol analysis and intention to treat analysis.

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