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Molecular chaperones and cell signalling
Title statement Molecular chaperones and cell signalling / edited by Brian Henderson, A. Graham Pockley. Varying form of title Molecular Chaperones & Cell Signalling Publication Cambridge : Cambridge University Press, 2005. Phys.des. 1 online resource (xiv, 330 pages) : digital, PDF file(s). ISBN 9780511546310 (ebook) Note Title from publisher's bibliographic system (viewed on 05 Oct 2015). Contents Chaperone function / R.J. Ellis -- Intracellular disposition of mitochondrial molecular chaperones / R.S. Gupta [and others] -- Novel pathways of protein secretion / G. Chimini, A. Rubartelli -- Moonlighting proteins / C.J. Jeffery -- Molecular chaperones / B. Henderson, A. Shamaei-Tousi -- Cell-cell signalling properties of the chaperonins / A.R.M. Coates -- Toll-like receptor-dependent activation of antigen presenting cells by Hsp60, Hsp70 and Gp96 / R.M. Vabulas, H. Wagner -- Regulation of signal transduction by intracellular and extracellular Hsp70 / A. Asea, S. Calderwood -- Hsp72 and cell signalling / M.Y. Sherman -- Heat shock proteins, their cell surface receptors and effect on the immune system / T. Lehner [and others] -- Molecular chaperone-cytokine interactions at the transcriptional level / A. Stephanou, D.S. Latchman -- Heat shock protein release and naturally-occurring exogenous heat shock proteins / J. Frostegård, A.G. Pockley -- Hsp27 as an anti-inflammatory protein / K. Laudanski, A. De, C. Miller-Graziano -- Bip, a negative immune regulator involved in rheumatoid arthritis / V.M. Corrigal, G.S. Panayi -- Neuroendocrine aspects of the molecular chaperones ADNF and ADNP / I. Gozes [and others] -- Heat shock proteins regulate by both molecular and network cross-reactivity / F.J. Quintana, I.R. Cohen -- Heat shock protein fusions / L. Mizzen, J. Neefe -- Molecular chaperones as inducers of tumour immunity / P.P. Banerjee, Z. Li -- Gazing into the crystal ball / L. Hightower. Notes to Availability Přístup pouze pro oprávněné uživatele Another responsib. Henderson, Brian (Professor), Pockley, A. Graham (Alan Graham), 1960- Subj. Headings Molecular chaperones. Form, Genre elektronické knihy electronic books Country Anglie Language angličtina Document kind Electronic books URL Plný text pro studenty a zaměstnance UPOL 
book
Originally published in 2005, this book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?
Chaperone function / R.J. Ellis -- Intracellular disposition of mitochondrial molecular chaperones / R.S. Gupta [and others] -- Novel pathways of protein secretion / G. Chimini, A. Rubartelli -- Moonlighting proteins / C.J. Jeffery -- Molecular chaperones / B. Henderson, A. Shamaei-Tousi -- Cell-cell signalling properties of the chaperonins / A.R.M. Coates -- Toll-like receptor-dependent activation of antigen presenting cells by Hsp60, Hsp70 and Gp96 / R.M. Vabulas, H. Wagner -- Regulation of signal transduction by intracellular and extracellular Hsp70 / A. Asea, S. Calderwood -- Hsp72 and cell signalling / M.Y. Sherman -- Heat shock proteins, their cell surface receptors and effect on the immune system / T. Lehner [and others] -- Molecular chaperone-cytokine interactions at the transcriptional level / A. Stephanou, D.S. Latchman -- Heat shock protein release and naturally-occurring exogenous heat shock proteins / J. Frostegård, A.G. Pockley -- Hsp27 as an anti-inflammatory protein / K. Laudanski, A. De, C. Miller-Graziano -- Bip, a negative immune regulator involved in rheumatoid arthritis / V.M. Corrigal, G.S. Panayi -- Neuroendocrine aspects of the molecular chaperones ADNF and ADNP / I. Gozes [and others] -- Heat shock proteins regulate by both molecular and network cross-reactivity / F.J. Quintana, I.R. Cohen -- Heat shock protein fusions / L. Mizzen, J. Neefe -- Molecular chaperones as inducers of tumour immunity / P.P. Banerjee, Z. Li -- Gazing into the crystal ball / L. Hightower.
Number of the records: 1