List of contributors -- Foreword / Myron L Weisfeldt MD -- Preface -- Part 1: Introduction: -- History of cardiopulmonary resuscitation / Mickey S Eisenberg, Peter Baskett, and Douglas Chamberlain -- Epidemiology of sudden death / Graham Nichol and David Baker -- Part 2: Basic Science: -- Global cellular ischemia/reperfusion during cardiac arrest: critical stress responses and the post resuscitation syndrome / Kim Hamann, Dave Beiser, and Terry L Vanden Hoek -- Genetics, genomics and proteomics in sudden cardiac death / Lesley A Kane, Silvia G Priori, Carlo Napolitano, Dan E Arking, and Jennifer E Van Eyk -- Intracellular signaling during myocardial ischemia / Peter H Sugden -- Electrophysiology of ventricular fibrillation and defibrillation / Wei Xiong and Gordon F Tomaselli -- Neuroendocrine response to global ischemia and reperfusion / Martin W Dunser, Stefan Jochberger, Karl-Heinz Stadlbauer, and Volker Wenzel -- Inflammatory and immunologic responses to ischemia and reperfusion / Jason S Haukoos, Ronald J Korthuis, and James T Niemann -- Resuscitation Research: -- Methodology of laboratory resuscitation research / Menekhem Zviman and Henry R Halperin -- Methodology of clinical resuscitation research / Johan Herlitz, Anouk van Alem, Volker Wenzel, and Karl Wegscheider -- Special problem of consent for resuscitation research / Henry R Halperin and Douglas Chamberlain -- Part 3: Pathophysiology Of Global Ischemia And Reperfusion: -- Etiology of sudden death / Sunil K Sinha, Arthur J Moss, and Hugh G Calkins -- Global brain ischemia and reperfusion / Brian J O'Neil, Robert W Neumar, Uwe Ebmeyer, and Gary S Krause -- Reperfusion injury in cardiac arrest and cardiopulmonary resuscitation / Thomas Aversano -- Visceral organ ischemia and reperfusion in cardiac arrest / Kevin R Ward And Andreas W Prengel -- Mechanisms of forward flow during external chest compression / Henry R Halperin -- Perfusion Pressures: -- Hemodynamics of cardiac arrest / Michael P Frenneaux and Stig Steen -- Coronary perfusion pressure during cardiopulmonary resuscitation / Karl B Kern, James T Niemann, and Stig Steen -- Methods to improve cerebral blood flow and neurological outcome after cardiac arrest / Uwe Ebmeyer, Laurence M Katz, and Alan D Guerci -- Pharmacology of cardiac arrest and reperfusion / Tommaso Pellis, Jasmeet Soar, Gavin Perkins, and Raul J Gazmuri -- Analysis and predictive value of the ventricular fibrillation waveform / Trygve Eftestol, Hans-Ulrich Strohmenger, and Colin Robertson -- Etiology, electrophysiology, and myocardial mechanics of pulseless electrical activity / Tom P Aufderheide -- Part 4: Therapy Of Sudden Death: -- Prevention of sudden cardiac death / Dominique M Ashen, and Roger S Blumenthal -- Sequence of therapies during resuscitation: application of CPR / Leonard A Cobb -- Transthoracic defibrillation / Richard E Kerber, Charles D Deakin, and Willis A Tacker, Jr -- Automated external defibrillators / Rudolph W Koster, Douglas Chamberlain, and Dianne L Atkins -- Public access defibrillation / Roger D White, Mick Colquhoun, Carys Sian Davies, Mary Ann Peberdy, and Sergio Timerman -- Physiology of ventilation during cardiac arrest and other low blood flow states / Ahamed H Idris and Andrea Gabrielli -- Airway techniques and airway devices / Jerry P Nolan and David A Gabbott -- External Chest Compression: Standard And Alternative Techniques: -- Manual cardiopulmonary resuscitation techniques / Henry R Halperin and Barry K Rayburn -- Mechanical devices for cardiopulmonary resuscitation / Henry R Halperin -- Invasive reperfusion techniques / Mark G Angelos -- Routes of drug administration / Thomas Kerz, Gideon Paret, and Holger Herff --Vasopressor Therapy During Cardiac Arrest: -- Adrenergic agonists / Max Harry Weil, Shijie Sun, and Wanchun Tang -- Vasopressin and other non-adrenergic vasopressors / Anette C Krismer, Martin W Dunser, Karl H Stadbauer, Karl H Lindner, and Volker Wenzel -- Antiarrhythmic therapy during cardiac arrest and resuscitation / Markus Zabel, Douglas Chamberlain, Paul Dorian, Peter Kudenchuk, Edward Platia, and Hans-Richard Arntz-- Acid-base considerations and buffer therapy / Gad Bar-Joseph, Fulvio Kette, Martin von Planta, and Lars Wiklund -- Cardiac arrest resuscitation monitoring / Kevin R Ward and Joseph Bisera -- Special considerations in the therapy of non-fibrillatory cardiac arrest / Tom P Aufderheide, Todd M Larabee, and Norman A Paradis -- Cardio cerebral resuscitation: a new approach to out-of-hospital cardiac arrest / Gordon A Ewy and Michael J Kellum -- Thrombolysis during resuscitation from cardiac arrest / Fabian Spohr and Bernd W Bottiger -- Percutaneous Coronary Intervention (PCI) after successful reestablishment of spontaneous circulation and during cardiopulmonary resuscitation / Marko Noc, Bjorn Bendz, and Karl B Kern -- Emergency medical services systems and out-of-hospital cardiac arrest / Matthias Fischer, Thomas Krafft, Luis Garcia-Castrillo Riesco, Freddy Lippert, Jerry Overton, and Iain Robertson-Steel -- In-hospital resuscitation / Mary Ann Peberdy, Johan Herlitz, and Michelle Cretikos -- Complications of CPR / Michael Baubin, Walter Rabl, and Robert Sebastian Hoke -- Bringing it all together: state-of-the-art- therapy of cardiac arrest / Max Harry Weil and Wanchun Tang -- Part 5: Post Resuscitation Disease and Its Care: -- Post Resuscitation syndrome / Erga L Cerchiari -- Prevention and therapy of post resuscitation myocardial dysfunction / Raul J Gazmuri, Max Harry Weil, Karl B Kern, Wanchun Tang, Iyad M Ayoub, Julieta Kolarova, and Jeejabai Radhakrishnan -- Prevention of post resuscitation neurologic dysfunction and injury by the use of the therapeutic mild hypothermia / Wilhelm Behringer, Stephen Bernard, Michael Holzer, Kees Polderman, Risto Roine, and Marjaana Tiainen -- Post resuscitation neurologic prognostication and declaration of brain death / Romergryko G Geocadin, Daniel F Hanley, and Scott M Eleff -- Bringing it all together: brain-oriented post resuscitation critical care / Uwe Ebmeyer, Laurence M Katz, Kevin R Ward, and Robert W Neumar -- Part 6: Special Resuscitation Circumstances: -- Prevention of sudden death in patients at risk: channelopathies and arrhythmic syndromes in the structurally normal heart / Alan Cheng, Gordon F Tomaselli, and Ronald D Berger -- Pediatric cardiopulmonary resuscitation / Robert A Berg and Vinay M Nadkarni -- Resuscitation in elder persons / Arthur B Sanders -- Asphyxial cardiac arrest / Peter Safar, Norman A Paradis, and Max Harry Weil -- Hemorrhagic shock and hypovolemic cardiac arrest / James L Atkins, Michael T Handrigan, And David Burris -- Cardiopulmonary resuscitation in hypothermic patients / Peter Mair, Birgit Schwarz, Beat Walpoth, and Tom Silfvast -- Cardiac arrest due to poisoning / Kenneth Heard and Norman A Paradis -- Cardiac arrest during anesthesia / Wolfgang Ummenhofer, Andrea Gabrielli, Quinn H Hogan, Eldar Soreide, and Mathias Zuercher -- Resuscitation of the pregnant patient suffering sudden cardiac death / Mark Stacey and Stephen Morris -- Drowning / Joost Bierens, Robert A Berg, Peter Morley, David Szpilman, and David S Warner -- Anaphylactic shock / Richard Pumphrey -- High altitude resuscitation / Philip Eisenburger, Benjamin Honigman, Susan Niermeyer, Robert Roach, and Wolfgang Voelckel -- Electrical injuries / Wolfgang Lederer, Erga Cerchiari, and Norman A Paradis -- Rare syndromes, commotio cordis, sudden death in athletes / Tommaso Pellis, Mark Link, Charles Antzelevitch, and Peter Kohl -- Part 7: Special Issues In Resuscitation: -- Ethics of resuscitation and end of life decisions / Peter Baskett, Arthur B Sanders, and Petter Andreas Steen -- Economics of treating sudden cardiac arrest / Alastair Fischer and Graham Nichol -- Medicolegal aspects / Richard Pawl -- Near-death experience, long-term psychological outcomes and support of survivors / Sam Parnia, K Spearpoint, and PB Fenwick -- CPR training / Michael Shuster, Walter Kloeck, Edward R Stapleton, Ulrik Juul Christensen, and Allan Braslow -- Consensus development in resuscitation: the growing movement towards international emergency cardiovascular care guidelines . Jerry P Nolan, D, Douglas Chamberlain, William H Montgomery, and Vinay M Nadkarni -- Index.