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3D cell-based biosensores in drug discovery programs
Title statement 3D cell-based biosensores in drug discovery programs [elektronický zdroj] : microtissue engineering for high throughput screening / William S. Kisaalita Additional Variant Titles Three-dimensional cell-based biosensors in drug discovery programs Personal name Kisaalita, William Ssempa, 1953- (author) Issue data Boca Raton, Fla. : CRC Press, c2010 Phys.des. xvii, 386 s. : il. ISBN 9781420073508 (e-book) Note Elektronická reprodukce. Palo Alto, Calif : ebrary, 2010 Subj. Headings farmakologie pharmacology * biotechnologie biotechnology * biosenzory biosensors Form, Genre elektronické knihy electronic books Conspect 615 - Farmacie. Farmakologie UDC 615.01/.09 , 60 , 577.3:681.586 , (0.034.2:08) Country Spojené státy americké Language angličtina Document kind Electronic sources URL http://site.ebrary.com/lib/upol/docDetail.action?docID=10408382
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information" -- Provided by publisher.