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poly(A)-vazebný protein II

  1. Topical termpoly(A)-vazebný protein II
    See linkPAB II (UF)
    PAB2 Poly(A) Binding Protein (UF)
    PABP2 (UF)
    Pabp2 Gene Product (UF)
    Pabp2 Protein (UF)
    Poly(A) Binding Protein II (UF)
    Poly(A) Binding Protein, Nuclear 1 (UF)
    See alsopoly(A)-vazebné proteiny
    svalová dystrofie okulofaryngeální (RT)
    Linking entryPoly(A)-Binding Protein II
    ConspectD12. - 776. - 157. - 725. - 452. - 500
    D12. - 776. - 664. - 962. - 452. - 500
    NoteA poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a minimum of ten ADENOSINE nucleotides in order for binding to mRNA. Once bound it works in conjunction with CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR to stimulate the rate of poly A synthesis by POLY A POLYMERASE. Once poly-A tails reach around 250 nucleotides in length poly(A) binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding protein II have been shown to cause the disease MUSCULAR DYSTROPHY, OCULOPHARYNGEAL.
    DatabaseMESH
    References (2) - MESH
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Number of the records: 1  

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