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proteiny spojené s mnohočetnou rezistencí k lékům

Topical term	proteiny spojené s mnohočetnou rezistencí k lékům
See link	ATP-Binding Cassette, Sub-Family C Proteins (UF)
	MOAT Protein (UF)
	Multidrug Resistance-Associated Protein (UF)
	Multispecific Organic Anion Transport Proteins (UF)
	Multispecific Organic Anion Transporter (UF)
See also	ABC transportéry
	přenašeče organických aniontů závislé na ATP
	protein CFTR
	protein spojený s mnohočetnou rezistencí k lékům 2
	mnohočetná léková rezistence (RT)
	P-glykoproteiny (RT)
Linking entry	Multidrug Resistance-Associated Proteins
Conspect	D12. - 776. - 157. - 530. - 100. - 304
	D12. - 776. - 157. - 530. - 450. - 074. - 500. - 500. - 500
	D12. - 776. - 543. - 585. - 100. - 304
	D12. - 776. - 543. - 585. - 450. - 074. - 500. - 500. - 500
Note	A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 family of proteins.
Database	MESH
References	(6) - MESH

subject heading

Number of the records: 1