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P-glykoproteiny

  1. Topical termP-glykoproteiny
    See linkABC transportér, podrodina B (UF)
    ATP Binding Cassette Transporter, Sub-Family B (UF)
    ATP-Binding Cassette, Sub-Family B Proteins (UF)
    efluxní transportéry (UF)
    Multidrug Resistance Proteins (UF)
    P-Glycoproteins (UF)
    proteiny vícečetné lékové rezistence (UF)
    transportní proteiny ABCB (UF)
    See alsoABC transportéry
    přenašeče organických aniontů závislé na ATP
    ABC transportér podrodiny B, člen 3
    ABC transportér, podrodina B, člen 11
    ABC transportér, podrodina B, člen 4
    P-glykoprotein
    peptidový transportér TAP1
    geny MDR (RT)
    mnohočetná léková rezistence (RT)
    proteiny spojené s mnohočetnou rezistencí k lékům (RT)
    rhodamin 123 (RT)
    Linking entryATP Binding Cassette Transporter, Subfamily B
    ConspectD09. - 400. - 430. - 890. - 020. - 400
    D12. - 776. - 157. - 530. - 100. - 075
    D12. - 776. - 157. - 530. - 450. - 074. - 500. - 500. - 250
    D12. - 776. - 395. - 550. - 020. - 400
    D12. - 776. - 543. - 550. - 192. - 400
    D12. - 776. - 543. - 585. - 100. - 200
    D12. - 776. - 543. - 585. - 450. - 074. - 500. - 500. - 250
    NoteA subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs (especially ANTINEOPLASTIC AGENTS) from cells, causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
    DatabaseMESH
    References (10) - MESH
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Number of the records: 1  

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