Number of the records: 1  

aflatoxin M1

  1. Topical termaflatoxin M1
    See link4-Hydroxyaflatoxin B1 (UF)
    Aflatoxin M (UF)
    Aflatoxin M(1) (UF)
    Aflatoxin M1, cis(+-)-Isomer (UF)
    See alsoaflatoxiny
    jedy (PA)
    Linking entryAflatoxin M1
    ConspectD03. - 383. - 663. - 283. - 119. - 100
    D03. - 633. - 100. - 150. - 119. - 100
    D23. - 946. - 587. - 142. - 100
    NoteA 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resulting from its P450 activation to the epoxide which alkylates DNA. Toxicity depends on the balance of liver enzymes that activate it (CYTOCHROME P-450) and others that detoxify it (GLUTATHIONE S TRANSFERASE) (Pharmac Ther 50.443 1991). Primates & rat are sensitive while mouse and hamster are tolerant (Canc Res 29.236 1969).
    DatabaseMESH
    References (1) - MESH
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Number of the records: 1  

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