Number of the records: 1

pre-B-buněčný leukemický transkripční faktor 1

Věcné téma	pre-B-buněčný leukemický transkripční faktor 1
Odkaz viz.	homeodoménový protein PBX1 (UF)
	homeoprotein PBX1 (UF)
	PBX1 Homeobox Protein (UF)
	Pre-B-Cell Leukemia Homeobox 1 Protein (UF)
Viz též	homeodoménové proteiny
	protoonkogenní proteiny
	transkripční faktory
Propojení	Pre-B-Cell Leukemia Transcription Factor 1
Konspekt	D12. - 776. - 260. - 400. - 836
	D12. - 776. - 624. - 664. - 700. - 163
	D12. - 776. - 930. - 712
Poznámka	A TALE-type homeodomain protein and transcription factor that binds the DNA sequence 5'-ATCAATCAA-3'. It forms a heterodimer with MEIS1 TRANSCRIPTION FACTOR and functions as a transcriptional activator of HOMEOBOX PROTEIN NKX-2.5 and ELONGIN A, and as a transcriptional repressor of CDKN2B PROTEIN, in the regulation of developmental and morphogenetic processes such as spleen and limb development. Chromosome translocations involving the PBX1 and TCF3 genes occur in cases of pre-B-cell ACUTE LYMPHOID LEUKEMIA.
Databáze	MESH
Odkazy	(3) - MESH

subject heading

Number of the records: 1