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serinová proteasa HTRA2

Topical term	serinová proteasa HTRA2
See link	HtrA Serine Peptidase 2 (UF)
	HtrA2 Protease (UF)
	Omi Serine Protease (UF)
	proteasa HtrA2 (UF)
	proteáza HtrA2 (UF)
	Serine Protease HTRA2 (UF)
	Serine Protease Omi (UF)
	serinová proteáza HTRA2 (UF)
	serinová proteáza Omi (UF)
See also	mitochondriální proteiny
	proteiny asociované s Parkinsonovou nemocí
	proteiny regulující apoptózu
	serinové endopeptidasy
	PDZ domény (RT)
Linking entry	High-Temperature Requirement A Serine Peptidase 2
Conspect	D08. - 811. - 277. - 656. - 300. - 760. - 431
	D08. - 811. - 277. - 656. - 959. - 350. - 431
	D12. - 776. - 476. - 075. - 429
	D12. - 776. - 575. - 656
	D12. - 776. - 705. - 625
Note	A serine peptidase that contains a C-terminal PDZ domain. It localizes to the mitochondrial membrane and intermembrane space, translocating to the cytoplasm following APOPTOSIS stimuli, such as UV irradiation; it promotes cell death by binding to and inhibiting INHIBITOR OF APOPTOSIS PROTEINS, resulting in an increase in activity of CASPASES. Mutations in the HTRA2 gene are associated with Type 13 PARKINSON DISEASE.
Database	MESH
References	(4) - MESH

subject heading

Number of the records: 1