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The Multiple Inert Gas Elimination Technique (MIGET)
Údaje o názvu The Multiple Inert Gas Elimination Technique (MIGET) [electronic resource] / by Susan R. Hopkins, Peter D. Wagner. Nakladatel Boston, MA : Springer US : Imprint: Springer, 2017. Fyz.popis XIII, 329 p. 56 illus., 24 illus. in color. online resource. ISBN 9781493974412 Edice Methods in Physiology Úplný obsah Chapter 1: Introduction and history -- Chapter 2: MIGET: Basic Physiological Principles -- Chapter 3: Mathematical Underpinnings -- Chapter 4: Strengths and Limitations from a Mathematical Perspective -- Chapter 5: Physiological Information Content of MIGET -- Chapter 6: MIGET: Practical Aspect -- chapter 7: Review of the MIGET Literature. Poznámky k dostupnosti Přístup pouze pro oprávněné uživatele Dal.odpovědnost Wagner, Peter D. Dal.odpovědnost SpringerLink (Online service) Předmět.hesla Medicine. * Human physiology. * Respiratory organs - Diseases. * Sports medicine. Forma, žánr elektronické knihy electronic books Země vyd. Spojené státy americké Jazyk dok. angličtina Druh dok. Elektronické knihy URL Plný text pro studenty a zaměstnance UPOL kniha
This is the first book to bring together the history, theory, mathematical approach, measurement details and limitations of the Multiple Inert Gas Elimination Technique (MIGET) and a summary of the global literature on its application in health and disease over the last 40 years. Up to the early 1970's, and despite substantial research carried out by leaders in respiratory physiology, it was not possible to measure the most important and most complex component of gas exchange in the lung: ventilation/perfusion (VA/Q) heterogeneity. Building on that earlier research, MIGET was developed to overcome this large gap in our understanding of the most important function of the lung. Just as CT and MRI make use of multiple, simultaneous imaging views to reconstruct the underlying anatomy spatially, MIGET uses the simultaneous exchange of six inert gases with differing blood solubility to reconstruct the functional distribution of VA/Q ratios. While the basic physiological principle of MIGET is straightforward, using inert gas exchange data to construct the VA/Q distribution requires complicated mathematics along with the ability to simultaneously measure the exchange of six foreign gases present in just parts per million or less. This unique book is a valuable resource for anyone interested in how the lung works.
Chapter 1: Introduction and history -- Chapter 2: MIGET: Basic Physiological Principles -- Chapter 3: Mathematical Underpinnings -- Chapter 4: Strengths and Limitations from a Mathematical Perspective -- Chapter 5: Physiological Information Content of MIGET -- Chapter 6: MIGET: Practical Aspect -- chapter 7: Review of the MIGET Literature.
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