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protoonkogenní proteiny c-abl
SYS d016315 LBL 01822nz--a2200301n--4500 003 CZ-PrNML 005 20240206162307.5 008 900619-n-ancnnbaba----------||-ana-----d 035 $a (DNLM)D016315 040 $a ABA008 $b cze $f czmesh 072 $a D08. $x 811. $x 913. $x 696. $x 620. $x 682. $x 725. $x 500 072 $a D12. $x 776. $x 476. $x 568. $x 500 072 $a D12. $x 776. $x 624. $x 664. $x 700. $x 167 150 $a protoonkogenní proteiny c-abl $2 czmesh 450 $w i $a abl Proto-Oncogene Products $i UF 450 $w i $a abl Proto-Oncogene Proteins $i UF 450 $w i $a c-abl Proteins $i UF 450 $w i $a Proto-Oncogene Proteins abl $i UF 550 $w g $a protoonkogenní proteiny $7 upol_us_auth*d011518 550 $w g $a tyrosinkinasy $7 upol_us_auth*d011505 550 $w h $a bcr-abl fúzové proteiny $7 upol_us_auth*d016044 550 $w i $a bcr-abl fúzové proteiny $i RT $7 upol_us_auth*d016044 680 $i Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation. 688 $a 91 750 -2
$a Proto-Oncogene Proteins c-abl $2 czmesh 980 $x M 982 $a 1
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