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The Actin Cytoskeleton

  1. Údaje o názvuThe Actin Cytoskeleton [electronic resource] / edited by Brigitte M. Jockusch.
    NakladatelCham : Springer International Publishing : Imprint: Springer, 2017.
    Fyz.popisXII, 352 p. 60 illus., 30 illus. in color. online resource.
    ISBN9783319463711
    EdiceHandbook of Experimental Pharmacology, ISSN 0171-2004 ; 235
    Úplný obsahFunctional significance of actin isoforms -- Assembly and maintenance of myofibrils in striated muscle cells -- Myosins: Domain organisation, motor properties, physiological roles and cellular functions -- Actin filament structures in migrating vertebrate cells -- Signalling pathways controlling cellular actin organization -- Actin-based endocytosis -- ADP-ribosylation and cross-linking of actin by bacterial protein toxins -- Common themes in cytoskeletal remodeling by intracellular bacterial effectors -- Viruses that exploit actin-based motility for their replication and spread -- Multiscale view of cytoskeletal mechanoregulation of cell and tissue polarity -- Molecular control of actin dynamics in vivo insights from Drosophila -- From cytoskeleton to gene expression – actin in the nucleus.
    Poznámky k dostupnostiPřístup pouze pro oprávněné uživatele
    Dal.odpovědnost Jockusch, Brigitte M.
    Dal.odpovědnost SpringerLink (Online service)
    Předmět.hesla Medicine. * Pharmacology. * Cell physiology.
    Forma, žánr elektronické knihy electronic books
    Země vyd.Německo
    Jazyk dok.angličtina
    Druh dok.Elektronické knihy
    URLPlný text pro studenty a zaměstnance UPOL
    kniha

    kniha


    Actin is one of the most abundant proteins and ubiquitously expressed in all eukaryotes. In recent years, the analysis of structure and function of such complexes has shed new light on actin's role in cellular and tissue morphogenesis, locomotion and various forms of intracellular motility, but also on its role in nuclear processes like chromatin architecture and transcription. Progress in understanding these different physiological phenomena, but also in unravelling the basis of actin-based pathophysiological processes has been made by combining video microscopy, molecular biology, genetics  and biochemistry. Thus, the current research on actin, as ongoing in many international laboratories, is a "hot spot" in basic and translational research in life sciences. In this book on  "The Actin Cytoskeleton", twelve internationally renowned authors present specific chapters that cover their recent work concerned with the various roles of actin mentioned above. This comprehensive volume is therefore an attractive handbook for teachers and students in many fields of medicine and pharmacology.

    Functional significance of actin isoforms -- Assembly and maintenance of myofibrils in striated muscle cells -- Myosins: Domain organisation, motor properties, physiological roles and cellular functions -- Actin filament structures in migrating vertebrate cells -- Signalling pathways controlling cellular actin organization -- Actin-based endocytosis -- ADP-ribosylation and cross-linking of actin by bacterial protein toxins -- Common themes in cytoskeletal remodeling by intracellular bacterial effectors -- Viruses that exploit actin-based motility for their replication and spread -- Multiscale view of cytoskeletal mechanoregulation of cell and tissue polarity -- Molecular control of actin dynamics in vivo insights from Drosophila -- From cytoskeleton to gene expression – actin in the nucleus.

Počet záznamů: 1  

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