Počet záznamů: 1
Effects of plant hormones on the lifespan of Caenorhabditis elegans
Údaje o názvu Effects of plant hormones on the lifespan of Caenorhabditis elegans [rukopis] / Alena Kadlecová Další variantní názvy Studium vlivu rostlinných hormonů na délku života Caenorhabditis elegans Osobní jméno Kadlecová, Alena (autor diplomové práce nebo disertace) Překl.náz Effects of plant hormones on the lifespan of Caenorhabditis elegans Vyd.údaje 2014 Fyz.popis 71 pages : il., grafy, tab. Poznámka Oponent Petr Džubák Ved. práce Jiří Voller Dal.odpovědnost Džubák, Petr (oponent) Voller, Jiří (vedoucí diplomové práce nebo disertace) Dal.odpovědnost Univerzita Palackého. Katedra buněčné biologie a genetiky (udelovatel akademické hodnosti) Klíč.slova Caenorhabditis elegans * aging * cytokinins * lifespan * Caenorhabditis elegans * aging * cytokinins * lifespan Forma, žánr diplomové práce master's theses MDT (043)378.2 Země vyd. Česko Jazyk dok. angličtina Druh dok. PUBLIKAČNÍ ČINNOST Titul Mgr. Studijní program Navazující Studijní program Biologie Studijní obor Molekulární a buněčná biologie kniha
Kvalifikační práce Staženo Velikost datum zpřístupnění 00179189-521489596.pdf 47 884 KB 30.04.2014 Posudek Typ posudku 00179189-ved-448148795.pdf Posudek vedoucího 00179189-opon-370744219.pdf Posudek oponenta Signatura Čár.kód Lokace Dislokace Info DP-KBB/120 (PřF-KBO) 3134517872 PřF-Holice PřF, Knihovna Holice - sklad pouze prezenčně
Caenorhabditis elegans is a useful source of information about aging. As an eukaryot, it shares several crucial aging-related conservative pathways with mammals including humans. It provides a more complex picture of biological processes than cell cultures and, compared to mammal models, it is much easier and cheaper to maintain in the laboratory. This and also many other advantages make it an ideal organism to use in basic biotechnological research and also for screenings of compounds with anti-aging potential. Cytokinins, plant hormones derived from adenine, are one group of such compounds. Some of them previously delayed senescence in cell cultures and also in flies. Moreover, they were able to suppress oxidative and glycation stress in mice. They have also been used in cosmetics for several years. However, cytokinins have never been tested on C. elegans. In this thesis, 5 compounds, either natural cytokinin bases or their synthetic derivatives, along with 2 cytokinin ribosides, were tested. The results of these experiments show that cytokinins are able to prolong the lifespan of C. elegans, possibly via hormesis.Caenorhabditis elegans is a useful source of information about aging. As an eukaryot, it shares several crucial aging-related conservative pathways with mammals including humans. It provides a more complex picture of biological processes than cell cultures and, compared to mammal models, it is much easier and cheaper to maintain in the laboratory. This and also many other advantages make it an ideal organism to use in basic biotechnological research and also for screenings of compounds with anti-aging potential. Cytokinins, plant hormones derived from adenine, are one group of such compounds. Some of them previously delayed senescence in cell cultures and also in flies. Moreover, they were able to suppress oxidative and glycation stress in mice. They have also been used in cosmetics for several years. However, cytokinins have never been tested on C. elegans. In this thesis, 5 compounds, either natural cytokinin bases or their synthetic derivatives, along with 2 cytokinin ribosides, were tested. The results of these experiments show that cytokinins are able to prolong the lifespan of C. elegans, possibly via hormesis.
Počet záznamů: 1