Počet záznamů: 1  

Effects of plant hormones on the lifespan of Caenorhabditis elegans

  1. Údaje o názvuEffects of plant hormones on the lifespan of Caenorhabditis elegans [rukopis] / Alena Kadlecová
    Další variantní názvyStudium vlivu rostlinných hormonů na délku života Caenorhabditis elegans
    Osobní jméno Kadlecová, Alena (autor diplomové práce nebo disertace)
    Překl.názEffects of plant hormones on the lifespan of Caenorhabditis elegans
    Vyd.údaje2014
    Fyz.popis71 pages : il., grafy, tab.
    PoznámkaOponent Petr Džubák
    Ved. práce Jiří Voller
    Dal.odpovědnost Džubák, Petr (oponent)
    Voller, Jiří (vedoucí diplomové práce nebo disertace)
    Dal.odpovědnost Univerzita Palackého. Katedra buněčné biologie a genetiky (udelovatel akademické hodnosti)
    Klíč.slova Caenorhabditis elegans * aging * cytokinins * lifespan * Caenorhabditis elegans * aging * cytokinins * lifespan
    Forma, žánr diplomové práce master's theses
    MDT (043)378.2
    Země vyd.Česko
    Jazyk dok.angličtina
    Druh dok.PUBLIKAČNÍ ČINNOST
    TitulMgr.
    Studijní programNavazující
    Studijní programBiologie
    Studijní oborMolekulární a buněčná biologie
    Kvalifikační práceStaženoVelikostdatum zpřístupnění
    00179189-521489596.pdf47884 KB30.04.2014
    PosudekTyp posudku
    00179189-ved-448148795.pdfPosudek vedoucího
    00179189-opon-370744219.pdfPosudek oponenta
    SignaturaČár.kódLokaceDislokaceInfo
    DP-KBB/120 (PřF-KBO)3134517872PřF-HolicePřF, Knihovna Holice - skladpouze prezenčně

    Caenorhabditis elegans is a useful source of information about aging. As an eukaryot, it shares several crucial aging-related conservative pathways with mammals including humans. It provides a more complex picture of biological processes than cell cultures and, compared to mammal models, it is much easier and cheaper to maintain in the laboratory. This and also many other advantages make it an ideal organism to use in basic biotechnological research and also for screenings of compounds with anti-aging potential. Cytokinins, plant hormones derived from adenine, are one group of such compounds. Some of them previously delayed senescence in cell cultures and also in flies. Moreover, they were able to suppress oxidative and glycation stress in mice. They have also been used in cosmetics for several years. However, cytokinins have never been tested on C. elegans. In this thesis, 5 compounds, either natural cytokinin bases or their synthetic derivatives, along with 2 cytokinin ribosides, were tested. The results of these experiments show that cytokinins are able to prolong the lifespan of C. elegans, possibly via hormesis.Caenorhabditis elegans is a useful source of information about aging. As an eukaryot, it shares several crucial aging-related conservative pathways with mammals including humans. It provides a more complex picture of biological processes than cell cultures and, compared to mammal models, it is much easier and cheaper to maintain in the laboratory. This and also many other advantages make it an ideal organism to use in basic biotechnological research and also for screenings of compounds with anti-aging potential. Cytokinins, plant hormones derived from adenine, are one group of such compounds. Some of them previously delayed senescence in cell cultures and also in flies. Moreover, they were able to suppress oxidative and glycation stress in mice. They have also been used in cosmetics for several years. However, cytokinins have never been tested on C. elegans. In this thesis, 5 compounds, either natural cytokinin bases or their synthetic derivatives, along with 2 cytokinin ribosides, were tested. The results of these experiments show that cytokinins are able to prolong the lifespan of C. elegans, possibly via hormesis.

Počet záznamů: 1  

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