Addiction from a clinical perspective -- The medical encounter: screening, confronting, and motivating -- Overview of addiction treatment -- Alcohol -- Sedative-hypnotics -- Opioids -- Tobacco -- Cocaine and other stimulants -- Phencyclidine and hallucinogens -- Marijuana -- Inhalants: volatile organic compounds, nitrites, and anesthetics -- Anabolic steroids and athletes -- Prescription drug abuse -- Medical care for the addicted patient -- Psychiatric illness and addiction -- Special populations.