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High-throughput screening methods in toxicity testing

  1. Údaje o názvuHigh-throughput screening methods in toxicity testing / edited by Pablo Steinberg
    NakladatelHoboken, New Jersey : John Wiley & Sons Inc., [2013?]
    Fyz.popis1 online zdroj
    ISBN9781118538180 (online ; pdf)
    1118538188
    9781118538203
    111853820X
    9781299252592
    1299252591
    Poznámky o skryté bibliografii a rejstřícíchObsahuje bibliografické odkazy a rejstřík
    Poznámky k dostupnostiPřístup pouze pro oprávněné uživatele
    PoznámkyZpůsob přístupu: World Wide Web
    DefektyeBooks on EBSCOhost
    Dal.odpovědnost Steinberg, Pablo (editor)
    Předmět.hesla farmakologie pharmacology * testování léků drugs testing * testy toxicity toxicity tests
    Forma, žánr elektronické knihy electronic books
    Konspekt615 - Farmacie. Farmakologie
    MDT 615.01/.09 , 615.9:57.08 , 615.038 , (0.034.2:08)
    Země vyd.New Jersey
    Jazyk dok.angličtina
    Druh dok.Elektronické zdroje
    URLhttp://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=542848
    kniha

    kniha


    "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--"This book describes the high-throughput in vitro methods available for toxicity testing, serving as a guide to scientists working in toxicity evaluation and risk assessment of chemicals and drugs"--

    pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.

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