Počet záznamů: 1
Identification and Characterization of Drug Resistance Mechanisms in cancer cells against Aurora Kinase Inhibitors CYC116 and ZM447439
Údaje o názvu Identification and Characterization of Drug Resistance Mechanisms in cancer cells against Aurora Kinase Inhibitors CYC116 and ZM447439 [rukopis] / Madhusudhan Reddy Kollareddy Další variantní názvy Identification and Characterization of Drug Resistance Mechanisms in Cancer cells against Aurora Kinase Inhibitors CYC116 and ZM447439 Osobní jméno Kollareddy, Madhusudhan Reddy (autor diplomové práce nebo disertace) Překl.náz Identification and Characterization of Drug Resistance Mechanisms in cancer cells against Aurora Kinase Inhibitors CYC116 and ZM447439 Vyd.údaje 2013 Poznámka Oponent Jiří Drábek Ved. práce Marián Hajdúch Oponent Marek Svoboda Dal.odpovědnost Drábek, Jiří, 1969- (oponent) Hajdúch, Marián (školitel) Svoboda, Marek, 1975- (oponent) Dal.odpovědnost Univerzita Palackého. Ústav patologie (udelovatel akademické hodnosti) Klíč.slova drug resistance * mechanisms * Aurora kinase inhibitors * CYC116 * ZM447439 * drug resistance * mechanisms * Aurora kinase inhibitors * CYC116 * ZM447439 Forma, žánr disertace dissertations MDT (043.3) Země vyd. Česko Jazyk dok. čeština Druh dok. PUBLIKAČNÍ ČINNOST Titul Ph.D. Studijní program Doktorský Studijní program Pediatrie Studijní obor Pediatrie 
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Kvalifikační práce Staženo Velikost datum zpřístupnění 00184758-631527812.pdf 15 21.9 MB 12.04.2013 Posudek Typ posudku 00184758-opon-284628931.pdf Posudek oponenta
This PhD thesis is focused on the identification of potential tumor cell resistance mechanisms to a novel Aurora kinase inhibitor CYC116, which has been tested in a Phase I clinical study. Alongside CYC116, we also included an experimental Aurora kinase inhibitor, ZM447439 to generate resistant HCT116 clones.This PhD thesis is focused on the identification of potential tumor cell resistance mechanisms to a novel Aurora kinase inhibitor CYC116, which has been tested in a Phase I clinical study. Alongside CYC116, we also included an experimental Aurora kinase inhibitor, ZM447439 to generate resistant HCT116 clones.
Počet záznamů: 1